Esketamine (Spravato) is the first rapid-acting medication for depression. It can work within hours. It’s also the first antidepressant in 30 years that works through a completely new mechanism.

Esketamine calms the part of the brain that’s responsible for anxious, self-critical, ruminative thoughts, called the default mode network.

Esketamine is the FDA approved ingredient in ketamine, a medicine that has been used successfully for mood disorders since the 1990’s.

Our authorization team will work with your insurance to help get this medicine covered

Esketamine is dosed through a nasal spray that’s given 1-2 times a week in the office. Why the office? One reason is safety. Esketamine can cause temporary drowsiness and out-of-body-like sensations called dissociation. Those symptoms usually go away within a few hours. Blood pressure can temporarily go up and needs to be monitored. Esketamine can be abused in large doses, and giving in the office prevents abuse and diversion.

The Mood Treatment Center is the first practice in the Triad to offer this ground-breaking therapy.

Esketamine is available at our Cambridge Plaza office at the corner of Country Club and Jonestown Rd in Winston-Salem

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“I never thought I’d find a place that really cares and knows what they’re doing like this place does.”

Google Reviewer

“I drive almost four hours to come to the Mood Treatment Center and it’s worth it. Warm, engaging, knowledgeable and responsive… the best care I’ve ever had.”

Google Reviewer

“Excellent care, short wait times, calming atmosphere!”

Google Reviewer

“As a medical professional, I can’t even put into words how impressed I am with The Mood Treatment Center. I’ve scheduled online, communicated by email, requested refills online and have had nothing but amazing, outstanding, exceptional service. I have been treated like I’m the only patient there.” 

−S.C., Facebook Reviewer

I came to the center in really bad shape. I am now able to have more positive control over my emotions. I am able to handle everyday life, and problems in a positive manner without getting so worked up. Thank you!” 

−M.L., Facebook Reviewer

After 30 years of misery… my life is the best it’s ever been! By far recommend this place to anyone and everyone that has any issues! For once I’ve found doctors that actually listen to me.” 

−P.K., Facebook Reviewer

“I really did not think a “mood treatment center” was for me; however, all that has changed. My life has improved and I now see that things I once thought were insurmountable are really just speed bumps.” 

−B.H., Facebook Reviewer

“I never received the correct treatment until I found the Mood Treatment Center. I am in such a better place now than I have been in 15 years.” 

−A.G., Facebook Reviewer

My psychiatrist at the Mood Treatment Center spent incredible amounts of time on the phone with me, and has given me wonderful advice and has literally saved my life.” 

Google Reviewer

I’ve seen a handful of counselors and two other psychiatrists over the past few years and none of them have compared to what I’ve found at the Mood Treatment Center. I feel like I’m finally getting my life back on track.” 

Google Reviewer

“I have never felt so backed by a treatment team before. By being in the same building, my psychiatrist and therapist are able to communicate about the best treatment plan for me.” 

Google Reviewer

“I have been to a lot of doctors and therapists and this place was the first that was really able to help me. It was nice to be able to get therapy and medication in the same place, and they don’t just push medication.” 

Google Reviewer

“When we found the Mood Treatment Center my son improved greatly. They got him on the right meds, encouraged him, and always had a kind word.” 

Google Reviewer

“They take a very holistic approach and don’t push medication. My therapist and doctor worked together to help me get off a lot of meds that I didn’t need.” 

Google Reviewer

“At the Mood Treatment Center they don’t just tell you what you have and what you have to take. They work with you. They helped me understand my diagnosis better and found a med that’s right for me. They’ve always responded to my questions and requests. When I email I usually get a response in a few hours, even on the weekend.”

Google Reviewer

“The Mood Treatment Center was a really warm place where I received care from someone who was both extremely knowledgeable and compassionate. The facility was comfortable and easy to find. I would highly recommend it!”

Google Reviewer

“My experience with the Mood Treatment Center and its staff has been great. From scheduling to therapy, I recommend them wholeheartedly.”

Google Reviewer

“Easiest new patient setup I’ve done.”

Google Reviewer